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The 2026 ADA guidelines suggest a promising role for these drugs in selected adults with type 1 diabetes and obesity

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13 RUCAM is a seven part investigative method for predicting the likelihood of causation between drug use and liver injury using a point system based on the relation to time of liver injury onset after drug use, the course of liver enzyme changes, risk factors, concomitant drug use, evaluation of alternative causes for liver injury, previously known drug hepatotoxicity, and response to unintentional re-exposure